Genetik Hastalık Tanı Laboratuvarlarında İş Sağlığı ve Güvenliği Eğitiminin Risk Yönetimi Üzerine Etkisi
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Abstract
This study investigates the critical influence of occupational health and safety (OHS) training programs on objective risk management outcomes among personnel working in genetic disease diagnostic laboratories. These specialized environments pose unique challenges, including exposure to complex biological agents, mutagenic chemicals, and high-energy equipment like thermal cyclers and sequencing machines. A cross-sectional survey was meticulously conducted among 60 laboratory personnel from 10 different diagnostic centers located in Istanbul, Turkey, utilizing a structured, validated questionnaire. The instrument focused on measuring training participation history, self-reported adherence to specific safety protocols, and proactive incident reporting behaviors. Data analysis, incorporating Pearson correlation, linear regression, and independent samples t-tests, revealed a substantial positive correlation. Personnel who had received formal, structured OHS training reported significantly higher comprehensive risk management scores (Mean=5.92, SD=0.48) compared to their untrained counterparts (Mean=4.78, SD=0.67; p<0.001). Moreover, the regression model indicated that training participation accounted for a substantial 42.3% of the variance in measured risk management performance (R²=0.423, p<0.001). In conclusion, these robust findings confirm that integrating mandatory, specialized safety education into continuous professional development is essential for ensuring stringent compliance, fostering a proactive safety culture, and mitigating occupational risks within high-risk genetic diagnostic settings.
Keywords
Abstract
This study investigates the critical influence of occupational health and safety (OHS) training programs on objective risk management outcomes among personnel working in genetic disease diagnostic laboratories. These specialized environments pose unique challenges, including exposure to complex biological agents, mutagenic chemicals, and high-energy equipment like thermal cyclers and sequencing machines. A cross-sectional survey was meticulously conducted among 60 laboratory personnel from 10 different diagnostic centers located in Istanbul, Turkey, utilizing a structured, validated questionnaire. The instrument focused on measuring training participation history, self-reported adherence to specific safety protocols, and proactive incident reporting behaviors. Data analysis, incorporating Pearson correlation, linear regression, and independent samples t-tests, revealed a substantial positive correlation. Personnel who had received formal, structured OHS training reported significantly higher comprehensive risk management scores (Mean=5.92, SD=0.48) compared to their untrained counterparts (Mean=4.78, SD=0.67; p<0.001). Moreover, the regression model indicated that training participation accounted for a substantial 42.3% of the variance in measured risk management performance (R²=0.423, p<0.001). In conclusion, these robust findings confirm that integrating mandatory, specialized safety education into continuous professional development is essential for ensuring stringent compliance, fostering a proactive safety culture, and mitigating occupational risks within high-risk genetic diagnostic settings.
